The company is also testing the drug in late-stage studies for chronicidiopathicconstipation.
2
Chronicidiopathicconstipation, especially the slow transit type, is a troubling problem often afflicting young women.
1
Dietary intakes of several foods were significantly associated with functionalconstipation.
2
This study assessed the efficacy and safety of mizagliflozin in patients with functionalconstipation.
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Other dietary patterns were not associated with functionalconstipation.
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Objectives: Patient-reported outcomes are necessary to evaluate the gastrointestinal symptom profile of patients with functionalconstipation.
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In contrast, analysis of dietary patterns may provide new insights into the influence of diet on functionalconstipation.
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The secondary objective compared the symptom profile of patients with functionalconstipation with patients with irritable bowel syndrome (IBS).
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The prevalence of functionalconstipation was 26.2%.
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Findings: Between Oct 15, 2014, and March 7, 2015, 258 patients with functionalconstipation were randomly assigned: 86 patients per group.
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Methods: Gastrointestinal Symptoms and Worry Scales were completed in a 9-site study by 116 pediatric patients with functionalconstipation and 188 parents.
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Functionalconstipation was defined using the Rome I criteria, which has previously been used in several epidemiologic studies on constipation.